CR-CEF-LB

Product Introduction CR-CEF-LB

• Cefixime, an antibiotic, is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases, may be susceptible to cefixime. The antibacterial effect of cefixime results from inhibition of mucopeptide synthesis in the bacterial cell wall.
• A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste.

Indication of CRCEF-LB

CRCEF-LB use in the treatment of the following infections when caused by susceptible strains of the designated microorganisms:

• Uncomplicated urinary tract infections caused by Escherichia coli and Proteus mirabilis,
• Otitis media caused by Haemophilus influenzae (beta-lactamase positive and negative strains), Moraxella catarrhalis (most of which are beta-lactamase positive), and S. pyogenes,
• Pharyngitis and tonsillitis caused by S. pyogenes,
• Acute bronchitis and acute exacerbations of chronic bronchitis caused by Streptococcus pneumoniae and Haemophilus influenzae (beta-lactamase positive and negative strains), and
• Uncomplicated gonorrhea (cervical/urethral) caused by Neisseria gonorrhoeae (penicillinase- and non-penicillinase-producing strains)..

Cefexime is indicated for respiratory tract infections, urinary tract infections and reproductive system infections as well as for other general abdominal infections including Typhoid.

Side Effects

• The main side effects are headache, dizziness, diarrhea, loose stools, abdominal pain, nausea, vomiting, dyspepsia & flatulence.