ACILET-SP (Aceclofenac 100mg,Paracetamol 325mg,Serratiopeptidase)

Benefit of Acilet-SP
Product Introduction
Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties. It is reported to have a higher anti-inflammatory action or at least comparable effects than conventional NSAIDs in double-blind studies.Aceclofenac potently inhibits the cyclo-oxygenase enzyme (COX) that is involved in the synthesis of prostaglandins, which are inflammatory mediators that cause pain, swelling, inflammation, and fever.

It is orally administered for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. Aceclofenac belongs to BCS Class II as it possesses poor aqueous solubility. Aceclofenac displays high permeability to penetrate into synovial joints where in patients with osteoarthritis and related conditions, the loss of articular cartilage in the area causes joint pain, tenderness, stiffness, crepitus, and local inflammation.Aceclofenac is also reported to be effective in other painful conditions such as dental and gynaecological conditions. Aceclofenac was developed as an analog of a commonly prescribed NSAID.

Propacetamol is a prodrug form of paracetamol which is formed from esterification of paracetamol, and the carboxylic acid diethylglycine. This has the advantage of making it.Paracetamol is a common painkiller used to treat aches and pain. It can also be used to reduce a high temperature.

Serrapeptase is a proteolytic enzyme preparation used concomitantly with an antibiotic in osteoarticular infections.

Indication of Acilet-SP
Aceclofenac Indicated for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.   Paracetamol For temporary relief of pain.
Serratiopeptidase(Serrapeptase) is used for painful conditions including back pain, osteoarthritis, rheumatoid arthritis, osteoporosis, fibromyalgia, carpel tunnel syndrome, migraine headache, and tension headache.

Side Effects
Common side effects are Nausea, vomiting, stomach pain, Indigestion, heartburn, loss of appetite and diarrhea.